Prevention and Attenuation of Covid-19 with the BNT162b2 and mRNA-1273 Vaccines
BACKGROUND
Information is limited regarding the effectiveness of the two-dose messenger RNA (mRNA) vaccines BNT162b2 (Pfizer–BioNTech) and mRNA-1273 (Moderna) in preventing infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and in attenuating coronavirus disease 2019 (Covid-19) when administered in real-world conditions.
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Public Health England: AstraZeneca COVID Shot 94% Protective Against Death in Over 65s
LONDON (Reuters) – Two doses of the Oxford/ AstraZeneca COVID-19 vaccine gives an estimated 94% protection against death from the disease in people over 65, Public Health England said on Thursday in a weekly surveillance report of real-world data.
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Impact of SARS-CoV-2 variants on the total CD4+ and CD8+ T cell reactivity in infected or vaccinated individuals
Highlights
T cells of exposed donors or vaccines effectively recognize SARS-CoV-2 variants
Effective recognition in AIM and FluoroSPOT assays, for spike and other proteins
93% and 97% of CD4 and CD8 epitopes are 100% conserved across variants
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CDC: Delta variant now 50% of US COVID-19 cases
By the end of the month, the Delta (B1617.2) variant will likely become an even more dominant strain of SARS-CoV-2 in the United States, as the more transmissible variant now accounts for 51.7% of all new COVID-19 cases in the country, CNN reports. The Alpha (B117) variant now accounts for 28.7% of cases.
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ApShiNi Ventures (www.apshini.org) donation of 1200 more co-ventillators have reached India and are being transferred to various government agencies and COVID – treating hospitals in India, with the help of local agencies like Healthcubed (www.healthcubed.com), Banglaworldwide (www.banglaworldwide.com) and Aarogya Seva (www.aarogyaseva.org), amongst various others.

We are also catering to requests from our AAPI members to donate to their hospitals back home. We still have some units to donate. Please email me if you know a hospital back in India who would use this in a not-for-profit manner.

Amit Chakrabarty MD, MS, FRCS
Chairman, ApShiNi Ventures